Presenting a green method in electrochemical synthesis of a new nitropropane derivative based on mefenamic acid

Document Type : Original Article

Authors

1 Faculty of Chemistry, University of Bu-Ali-Sina, Hamedan, Iran 65178-38683, Iran

2 University of Bu-Ali-Sina, Campus of Nahavand, Nahavand, Iran

10.22036/cr.2022.294454.1152

Abstract

In the present study, the electrochemical behavior of mefenamic acid in the presence of 2-nitropropane (2-NP) was studied in buffer solution /ethanol ( 70:30 v/v) in pH=10 by using of cyclic voltammetry and controlled-potential-coulometry techniques. In this situation mefenamic acid (MFA) was used as electrophile in the synthesis of nitropropane derivative based on the mefenamic acid. The results showed that the 2-nitropropane (2-NP) group in the solution attacked the intermediate resulting from mefenamic acid oxidation and resulted in the formation of 2 ((3,2-dimethyl-6- (2-nitropropane-2-yl) phenyl) amino) benzoic acid (MNP) as a new product via michael addition reaction. On the other hand, the electrochemical behavior of this new produce (MNP) and its dye properties were investigated and confirmed as a textile acid dye. Our results show that this new product can be used as an acidic color in dyeing fabrics. Also, two different crystals of 2-nitropropane dimer were obtained and identified by electrochemical oxidation of 2-nitropropane (2-NP) in the absence and presence of mefnamic acid (MFA).

Graphical Abstract

Presenting a green method in electrochemical synthesis of a new nitropropane derivative based on mefenamic acid

Keywords

References

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Iranian Journal of Chemistry
Volume 4, Issue 2 - Serial Number 7
February 2022
Pages 179-185

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History

  • Receive Date: 13 July 2021
  • Revise Date: 17 January 2022
  • Accept Date: 09 February 2022

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