نوع مقاله : مقاله پژوهشی
نویسندگان
1 گروه شیمی، دانشکده علوم، دانشگاه سیستان و بلوچستان، زاهدان، ایران
2 دانشکده علوم، دانشگاه ولایت، ایرانشهر، ایران
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
In this work, one-pot synthesis of dihydropyrano[2,3-c]pyrazole and pyrazolopyranopyrimidine derivatives from the reaction between aromatic aldehydes, ethyl acetoacetate, hydrazine hydrate, and malononitrile or barbituric acid in the presence of vitamin A as a heterogeneous, green and eco-friendly catalyst is discussed. mild reaction conditions, avoiding the use of any hazardous and toxic solvents, high yield, operational simplicity, simple work up without need to column chromatography are some of benefits present method in synthesis of this biologically compounds.
In this work, one-pot synthesis of dihydropyrano[2,3-c]pyrazole and pyrazolopyranopyrimidine derivatives from the reaction between aromatic aldehydes, ethyl acetoacetate, hydrazine hydrate, and malononitrile or barbituric acid in the presence of vitamin A as a heterogeneous, green and eco-friendly catalyst is discussed. mild reaction conditions, avoiding the use of any hazardous and toxic solvents, high yield, operational simplicity, simple work up without need to column chromatography are some of benefits present method in synthesis of this biologically compounds.
کلیدواژهها [English]
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